General time-encoding description and improved RASER imaging

نویسندگان

  • R. Chamberlain
  • M. Garwood
چکیده

Rapid acquisition by sequential excitation and refocusing (RASER) is a new ultrafast MRI technique (1). It provides single-shot images that are purely T2-weighted, so there are no artifacts due to T2 * effects that plague EPI. RASER shows promise for fMRI studies in areas of the brain that are difficult to image with EPI (2, 3). The basis of RASER is time-encoding, which uses a frequency-swept excitation pulse to encode one dimension of the image (1, 4, 5). All previously reported versions of time-encoding use a chirp pulse, which has a poor slab-selection profile. In this work, we provide a general description of time-encoding for any excitation pulse with frequency and gradient modulation, along with an analysis of the SNR possible with time-encoding, and a comparison of the time-encoded signal produced by chirp, HS20, and HS40 pulses.

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تاریخ انتشار 2008